Saint Paul, MN

AMERICAN INDIAN CANCER FOUNDATION

EIN 27-0300026

Health & Wellness Disease & Chronic Illness Support Indigenous communities

Mission

To eliminate the cancer burdens of Indigenous people through improved access to prevention, early detection, treatment, and survivor support.

IRS-recognized 501(c)(3) public charity Contributions are tax-deductible

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About AMERICAN INDIAN CANCER FOUNDATION

The American Indian Cancer Foundation (AICAF) is a Native-led national 501(c)(3) nonprofit based in Saint Paul, Minnesota, founded to address cancer inequities affecting American Indian and Alaska Native (AI/AN) communities. AICAF builds culturally tailored programs across the cancer continuum—prevention, screening, treatment access, survivorship, research, and policy—working with tribal, clinical, and public-health partners. In recent years AICAF has expanded its resource library, hosted webinars and community events, supported community-based research, and launched initiatives to improve access to specialty care and clinical trials tailored for Indigenous people. The organization uses community-based participatory approaches and culturally grounded materials to increase screening, support survivors, and strengthen local tribal health capacity.

Notable achievements

Powwow for Hope — annual community fundraiser

AICAF’s Powwow for Hope is a longstanding community healing event and fundraiser that brings together Indigenous families and supporters; recent annual events have raised substantial community funds to support AICAF programming (the 2023 event raised six-figure support reported in the organization’s annual materials).

Culturally tailored resources & toolkits

Developed and disseminated culturally grounded education materials, recorded webinar series (e.g., nutrition and screening webinars), and a Community Health Assessment Toolkit to help tribal and urban Indian health programs increase prevention and screening uptake.

Research, evaluation and clinical-trials access work

Sustained research and evaluation activities (including community-based studies on lung and other cancer screening) and recent efforts to improve equitable access to specialty care and clinical trials for Indigenous patients through tailored resources and provider engagement.

At a glance

Total assets: $1.5M
Annual revenue: $2.4M
Tax status: 501(c)(3)Public charity
EIN: 27-0300026
Location: Saint Paul, MN
Website: americanindiancancer.org
On Mahalo since: September 2026

Financial figures from the IRS Business Master File, the IRS’s registry of tax-exempt organizations.

Recognition

Recognized by Charity Navigator for transparency and strong disclosure on financial and accountability metrics (high scores on public tax-form disclosure and related accountability indicators).

Partnered with federal and public-health initiatives and tribal coalitions to advance cancer equity, including work aligned with community health and CDC-supported approaches.

Featured in professional oncology and community-health discussions for its work on improving clinical-trials participation and culturally relevant cancer resources for AI/AN communities.

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