Dallas, TX

The Osteosarcoma Institute

EIN 82-2921815

Health & Wellness Medical Research & Training Children & youth Patients & families

Mission

To dramatically increase treatment options and survival rates in osteosarcoma patients by identifying, funding, and accelerating the most promising clinical trials and scientific research.

IRS-recognized 501(c)(3) public charity Contributions are tax-deductible

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About The Osteosarcoma Institute

The Osteosarcoma Institute is a U.S.-based 501(c)(3) nonprofit that funds and coordinates research and clinical trials specifically focused on osteosarcoma, with an emphasis on improving outcomes for relapsed and metastatic patients. ([osinst.org](https://osinst.org/about/?utm_source=openai))

Since receiving tax-exempt status in 2018, the Institute has grown into a grantmaking and programmatic funder that partners with major cancer and research centers to support translational research, correlative science, and clinical trials. Recent activity includes multi-hundred-thousand-dollar commitments to trials and translational projects with academic partners. ([osinst.org](https://osinst.org/wp-content/uploads/2024/10/2023-Form-990-The-Osteosarcoma-Institute.pdf?utm_source=openai))

Notable achievements

Substantial fundraising and assets growth

Reported fiscal-year revenues in excess of $4 million and net assets growing into the multi‑million-dollar range, enabling larger multi-institution grantmaking and trial support.

Major multi-institution grant awards

Executed and funded multi‑year grants and clinical-trial support agreements with leading institutions (including multi-hundred-thousand-dollar commitments to translational and clinical programs during 2023–2024). ([causeiq.com](https://www.causeiq.com/organizations/the-osteosarcoma-institute%2C822921815/?utm_source=openai))

Dedicated osteosarcoma-focused research investments

Established targeted grant programs supporting correlative science and translational projects aimed at increasing available therapies for metastatic and relapsed osteosarcoma patients.

At a glance

Total assets: $6.3M
Annual revenue: $4.2M
Tax status: 501(c)(3)Public charity
EIN: 82-2921815
Location: Dallas, TX
Website: osinst.org
On Mahalo since: September 2026

Financial figures from the IRS Business Master File, the IRS’s registry of tax-exempt organizations.

Recognition

Four‑star (91%) rating on Charity Navigator, indicating strong performance on Charity Navigator’s evaluation metrics.

Listed and tracked by nonprofit data services (ProPublica Nonprofit Explorer, CauseIQ, Grant databases) with publicly available Form 990s documenting activity and grantmaking.

Recognized partner by academic cancer centers and research groups for targeted osteosarcoma funding and trial support.

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